mRNA vaccines

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mRNA vaccines and therapeutics require less money to produce as compared to traditional medicines. They also offer higher effectiveness and enhanced immunogenicity. The vaccines are developed with the help of advanced technologies, having more efficacy against pathogens.

Infectious diseases such as HIV and chronic diseases like cancer, cardiovascular disorders, and diabetes will make the market for mRNA vaccines grow rapidly. The world sees surging demand for vaccines for influenza, Ebola, HIV, and other viral illnesses. Coupled with the inability of conventional methods to find vaccines on time will likewise spur market growth.

How mRNA vaccines compare to traditional vaccines

Inside the mRNA engine room

messenger RNA (mRNA) vaccine is a type of vaccine that uses a copy of a natural molecule called messenger RNA(mRNA) to produce an immune response. The vaccine transfects molecules of synthetic RNA into immunity cells. Once inside the immune cells, the vaccine’s RNA functions as mRNA, causing the cells to build the foreign protein. This would normally be produced by a pathogen (such as a virus) or by a cancer cell. These protein molecules stimulate an adaptive immune response which teaches the body how to identify and destroy the corresponding pathogen or cancer cells. The delivery of mRNA is achieved by a co-formulation of the molecule into lipid nanoparticles. They protect the RNA strands and helps their absorption into the cells.

Higher production speed and lower cost

The advantages of RNA vaccines over traditional protein vaccines are superior design and production speed. But also a lower cost of production, and the induction of both cellular as well as humoral immunity. The Pfizer–BioNTech COVID-19 vaccine requires ultracold storage before distribution. Other mRNA vaccines do not, such as the COVID-19 vaccines by ModernaCureVac and Walvax.

See how the mRNA vaccines work
Moderna personalized mRNA based cancer vaccines